Assessment of Atrial Electromechanical Coupling Characteristics and P-Wave Dispersion in Patients with Atrial Septal Aneurysm

摘要

Objective: The aim of this study was to evaluate atrial conduction abnormalities obtained by Doppler tissue imaging (DTI) and electrocardiogram analysis in Atrial septal aneurysm (ASA) patients.Methods: A total of 30 patients with ASA (11 males/19 females, mean age 29.6 +-11.3 years) and 25 controls (9 males/16 females, mean age 27.6 +- 9.98 years) were included. Interatrial and intraatrial electromechanical coupling (PA) intervals were measured with DTI. P-wave dispersion (Pd) was calculated from the 12-lead electrocardiogram. Systolic and diastolic left ventricular (LV) functions were measured by using conventional echocardiography and DTI. Results: Atrial electromechanical coupling at the left lateral mitral annulus (PA lateral) was significantly delayed in ASA patients ( 59.3 +-4.2 vs 48.5 +- 1.1 ms, P < 0.0001). Interatrial (PA lateral - PA tri-cuspid) and intraatrial (PA septum - PA tricuspid) electromechanical coupling interval were significantly longer in ASA patients (26.1 +- 6.2 vs 14.4 +- 6.75 ms, P < 0.0001 and 9.04 +- 1.1 vs 5.4 +- 2.5 ms, P < 0.0001). maximum P-wave (Pmax) duration and Pd were significantly longer in ASA patients (98.3 +- 8.1 vs 86.4 +- 7.8 ms, P < 0.001 and 20.7 +- 0.9 vs 12.3 +- 1.5, P < 0.0001). Systolic and diastolic left ventricular functions of both groups were comparable. Conclusion: This study shows that atrial electromechanical coupling intervals and Pd are delayed in ASA patients.