The Aminohydroxylation of Alkenes Breaks New Ground

摘要

β-Amino alcohols constitute an important scaffold in many natural and synthetic molecules with diverse applications as drugs, fine chemicals, and catalysts. Prominent examples include the cell signalling molecule sphingosine, the HIV protease inhibitor saquinavir, the sympathomimetic ephedrine, prolinol-based organocatalysts, and the so-called Evans auxiliary.