Palladium-Catalyzed Enantioselective Hydrosilylation of Aromatic Olefins

摘要

Asymmetric catalytic hydrosilylation represents a versatile synthetic tool for the refinement of prochiral alkenes. The resul ting organosilicon products can be easily functionalized, for example, by stereospecific Tamao-Fleming oxidation to afford chiral alcohols with retention of the absolute configuration. In general, simple terminal aliphatic olefins give linear, nonchi-ral products. Conversely, hydrosilylation of aromatic olefins leads to the selective formation of the branched Markovnikov products.