Bead-Based Cellular Analysis,Sorting and Multiplexing

摘要

Cellular entry is important for the delivery of potential drugs,small-molecule modulators and sensors.Recently attention has focused on the development of a diverse range of specific delivery systems in order to enhance transport and uptake at the cellular level.Contemporary examples of delivery vectors include peptides,such as those based on fragments derived from the Tat protein,peptidomimetic carriers,such as those based on polymers and dendrimers,and various physical methods,such as micro-injection.Polymer-mediated delivery offers many advantages;for instance,polymeric materials can allow the controlled delivery and release of their cargo at controllable local concentrations.