Efficacy of Fenbendazole Against Giardiasis in Dogs

摘要

Giardiasis is a relatively common, serious, and possibly zoonotic disease of many companion animals and livestock. The drug of choice for treatment of giardiasis in dogs has been metronidazole. However, this drug is only approximately 67% effective and may cause neurotoxicosis in some animals. The benzimidazole car-bamate derivative albendazole is approximately 50 times more effective against Giardia in vitro than is metronidazole, and fenbendazole, another benzimidazole, has shown similar efficacy.The efficacy of fenbendazole in the treatment of naturally acquired giardiasis in dogs was investigated.