The molecular typing data of recently identified subtype 11q/j of treponema pallidum subsp. pallidum suggest imported case of yaws

摘要

In the article "Molecular Subtyping of Treponema pallidum in Paris, France," published in Sexually Transmitted Diseases journal (Vol. 40, No. 8, August 2013), Grange et al.1 identified 3 subtypes that are sporadically present in the human population. that is, subtypes llq/j, 14d/d, and 15d/f. Interestingly, subtype 1 lq/j showed a unique typing pattern "q" corresponding to a new restriction profile after Msel digestion of the tprE, G,J genes (Centers for Disease Control and Prevention [CDC] typing system)2 and "j" corresponding to a new sequence type within the 83-base-pair region of the tpO548 gene (enhanced CDC typing system).3 This genital specimen was isolated from an HIV-negative MSM (men who have sex with men) patient with diagnosed primary syphilis.