Endothelial Jag1-RBPJ signalling promotes inflammatory leucocyte recruitment and atherosclerosis

Nus Meritxell; Martinez-Poveda Beatriz; MacGrogan Donal; Chevre Rafael; DAmato Gaetano; Sbroggio Mauro; Rodriguez Cristina; Martinez-Gonzalez Jose; Andres Vicente; Hidalgo Andres; Luis de la Pompa Jose

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Endothelial Jag1-RBPJ signalling promotes inflammatory leucocyte recruitment and atherosclerosis

机译：内皮Jag1-RBPJ信号传导促进炎症性白细胞募集和动脉粥样硬化

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摘要

To determine the role of NOTCH during the arterial injury response and the subsequent chronic arterial-wall inflammation underlying atherosclerosis.

机译：要确定NOTCH在动脉损伤反应和随后的动脉粥样硬化潜在的慢性动脉壁炎症反应中的作用。

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来源
《Cardiovascular Research》 |2016年第2期|共13页
作者
Nus Meritxell; Martinez-Poveda Beatriz; MacGrogan Donal; Chevre Rafael; DAmato Gaetano; Sbroggio Mauro; Rodriguez Cristina; Martinez-Gonzalez Jose; Andres Vicente; Hidalgo Andres; Luis de la Pompa Jose;
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正文语种 eng
中图分类心脏、血管（循环系）疾病;
关键词
Atherosclerosis; Endothelium; Inflammation; Notch; NF-kappa B; Transcriptional regulation;

机译：动脉粥样硬化;内皮;炎症;刻痕;NF-κB;转录调控;

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专利

1. Endothelial Jag1-RBPJ signalling promotes inflammatory leucocyte recruitment and atherosclerosis [J] . Nus Meritxell, Martinez-Poveda Beatriz, MacGrogan Donal, Cardiovascular Research . 2016,第2期

机译：内皮Jag1-RBPJ信号传导促进炎症性白细胞募集和动脉粥样硬化
2. Androgen receptor (AR) signaling promotes RCC progression via increased endothelial cell proliferation and recruitment by modulating AKT?→?NF-κB?→?CXCL5 signaling [J] . Zhenfeng Guan, Chong Li, Jinhai Fan, Scientific reports. . 2016,第1期

机译：雄激素受体（AR）信号通过调节AKT？→？NF-κB？→？CXCL5信号通过促进内皮细胞增殖和募集来促进RCC进展
3. Myeloid type I interferon signaling promotes atherosclerosis by stimulating macrophage recruitment to lesions. [J] . Goossens P, Gijbels MJ, Zernecke A, Cell metabolism . 2010,第2期

机译：髓样I型干扰素信号传导通过刺激巨噬细胞募集至病变而促进动脉粥样硬化。
4. Fundamental Roles in the Inflammatory Response: Winding the Way to the Pathogenesis of Endothelial Dysfunction and Atherosclerosis [C] . RAVICHANDRAN RAMASAMY, SHI FANG YAN, KEVAN HEROLD, International Symposium on the Maillard Reaction . 2008

机译：炎症反应中的基本作用：缠绕到内皮功能障碍和动脉粥样硬化的发病机制
5. Study of the role of activin receptor like kinase-1 signaling in control of vascular endothelial growth factor expression and atherosclerosis. [D] . Shao, Esther Szu-Chia. 2009

机译：研究激活素受体（如激酶-1）在控制血管内皮生长因子表达和动脉粥样硬化中的作用。
6. Androgen receptor (AR) signaling promotes RCC progression via increased endothelial cell proliferation and recruitment by modulating AKT → NF-κB → CXCL5 signaling [O] . Zhenfeng Guan, Chong Li, Jinhai Fan, -1

机译：雄激素受体（AR）信号通过调节AKT→NF-κB→CXCL5信号通过促进内皮细胞增殖和募集来促进RCC进展
7. Endothelial Jag1-RBPJ signalling promotes inflammatory leucocyte recruitment and atherosclerosis [O] . Meritxell Nus, Beatriz Martínez-Poveda, Donal MacGrogan, 2016

机译：内皮JAG1-RBPJ信号促进炎症性白细胞募集和动脉粥样硬化

Endothelial Jag1-RBPJ signalling promotes inflammatory leucocyte recruitment and atherosclerosis

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