Lipocalin-2 deficiency or blockade protects against aortic abdominal aneurysm development in mice

Tarin Carlos; Ernesto Fernandez-Garcia Carlos; Burillo Elena; Pastor-Vargas Carlos; Llamas-Granda Patricia; Castejon Borja; Ramos-Mozo Priscila; Torres-Fonseca Monica M.; Berger Thorsten; Mak Tak W.; Egido Jesus; Blanco-Colio Luis M.; Martin-Ventura Jose L.

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Lipocalin-2 deficiency or blockade protects against aortic abdominal aneurysm development in mice

机译：Lipocalin-2缺乏或受阻可预防小鼠腹主动脉瘤的发展

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摘要

To study the role of lipocalin-2 (Lcn2) and the effect of Lcn2 blockade via anti-Lcn2 antibody in the development of abdominal aortic aneurysm (AAA).

机译：研究lipocalin-2（Lcn2）的作用以及通过抗Lcn2抗体阻断Lcn2在腹主动脉瘤（AAA）发展中的作用。

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来源
《Cardiovascular Research》 |2016年第3期|共12页
作者
Tarin Carlos; Ernesto Fernandez-Garcia Carlos; Burillo Elena; Pastor-Vargas Carlos; Llamas-Granda Patricia; Castejon Borja; Ramos-Mozo Priscila; Torres-Fonseca Monica M.; Berger Thorsten; Mak Tak W.; Egido Jesus; Blanco-Colio Luis M.; Martin-Ventura Jose L.;
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正文语种 eng
中图分类心脏、血管（循环系）疾病;
关键词
Abdominal aortic aneurysm; Lcn2; PMN; MMP;

机译：腹主动脉瘤;Lcn2;PMN;MMP;

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专利

1. Lipocalin-2 deficiency or blockade protects against aortic abdominal aneurysm development in mice [J] . Tarin Carlos, Ernesto Fernandez-Garcia Carlos, Burillo Elena, Cardiovascular Research . 2016,第3期

机译：Lipocalin-2缺乏或受阻可预防小鼠腹主动脉瘤的发展
2. Angiotensin II Type 1 Receptor Blockade With Losartan Attenuates Abdominal Aortic Aneurysm Development in Spontaneously Hypertensive Mice [J] . Ward Nicholas, Grespin Randal, Couch Christine, Journal of vascular surgery . 2019,第6期

机译：血管紧张素II型1受体封锁与洛萨顿患者在自发性高血压小鼠中衰减腹主动脉瘤发育
3. High serum thrombospondin-1 concentration is associated with slower abdominal aortic aneurysm growth and deficiency of thrombospondin-1 promotes angiotensin II induced aortic aneurysm in mice [J] . Krishna Smriti Murali, Seto Sai Wang, Jose Roby, Clinical Science . 2017,第11a12期

机译：高血清血栓活性素-1浓度与较慢的腹主动脉瘤生长和血压出素-1的缺乏促进血管紧张素II诱导小鼠的主动脉瘤诱导的主动脉瘤
4. Pulse Wave Imaging Of Abdominal Aortic Aneurysms - Comparison Between Control And Angiotensin II-Treated Mice In Vivo [C] . Jianwen Luo, Kana Fujikura, Leslie S. Tyrie, IEEE Ultrasonics Symposium . 2007

机译：腹主动脉瘤的脉波成像 - 体内对照和血管紧张素II处理小鼠的比较
5. Polymeric endo-aortic paving (PEAP): Initial development of a novel treatment for abdominal aortic aneurysms [D] . Ashton, John H. 2010

机译：聚合主动脉内铺路（PEAP）：腹主动脉瘤的新型治疗方法的初步开发
6. CD1d deficiency inhibits the development of abdominal aortic aneurysms in LDL receptor deficient mice [O] . Gijs H. M. van Puijvelde, Amanda C. Foks, Rosemarie E. van Bochove, -1

机译：CD1d缺乏抑制LDL受体缺乏小鼠的腹主动脉瘤的发展
7. Lipocalin-2 deficiency or blockade protects against aortic abdominal aneurysm development in mice [O] . Carlos Tarín, Carlos Ernesto Fernandez-Garcia, Elena Burillo, 2016

机译：Lipocalin-2缺乏或阻断保护小鼠中的主动脉腹部动脉瘤发育

Lipocalin-2 deficiency or blockade protects against aortic abdominal aneurysm development in mice

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