Chronic hepatitis C of 28 years' duration characterized by early development of stage 2 (of 4) fibrosis but no significant progression over the subsequent 18 years.

摘要

A 29-year-old attorney was referred to one of the authors (P.D.B.) at Sinai Medical Center (New York) on July 1,1982 with jaundice, malaise, nausea, vomiting, and diffuse ecchymoses. The ecchymoses developed several days earlier after the patient slid into second base during a softball game between New York law firms. The other symptoms evolved over the subsequent 24 hours. Although his symptoms were thought by his referring physician to reflect an acute hepatitis, the absence of bilirubin from the urine during his initial outpatient evaluation pointed toward a hemolytic rather than a hepatic cause for the jaundice.