An update on the thrombotic microangiopathies hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP)

摘要

Welcome to this special issue of Seminars in Thrombosis & Hemostasis, which summarizes up-to-date knowledge on pathogenesis, diagnosis, and treatment of thrombotic micro-angiopathies (TMAs) such as (enterohemorrhagic) ￡ coli (EHEC)-associated hemolytic uremic syndrome (HUS) (eHUS), atypical HUS (aHUS), (aHUS) and thrombotic throm-bocytopenic purpura (TTP). This issue also reviews C3 glo-merulopathies (C3G), emphasizing the expanding spectrum of TMAs.