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Heart Transplantation in Children after a Fontan Procedure: Better than People Think

机译:丰坦手术后的儿童心脏移植:比人们想象的要好

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Previous studies have reported that children with a prior Fontan procedure have decreased survival after heart transplantation. We examined 273 primary pediatric heart transplants. Since 1988, 33 (12.1%) of 273 children <18 years old undergoing primary heart transplantation had a Fontan procedure 3.7 +- 4.3 years before transplantation. Compared with 240 (87.9%) non-Fontan primary transplants, the Fontan patients were older (8.8 +- 5.2 vs6.6 +- 5.9 years; P=023), but were similar in presensitization and pre-transplant clinical status. More Fontan patients had prior operations (100% vs 51.7%; P < .0001) and needed pulmonary artery reconstruction (100% vs2 .7%; P < .0001). Thirteen (39%) had protein-losing enteropathy. and
机译:先前的研究报道,先有丰坦手术的儿童心脏移植后存活率降低。我们检查了273例原发性小儿心脏移植。自1988年以来,接受心脏移植的273名<18岁儿童中有33名(12.1%)在移植前3.7±4.3年接受了Fontan手术。与240例(87.9%)非方丹原发移植相比,Fontan患者年龄更大(8.8±5.2 vs6.6±5.9岁; P = 023),但在敏化前和移植前的临床状况相似。有更多接受手术的Fontan患者(100%vs 51.7%; P <.0001)并需要进行肺动脉重建(100%vs2。.7%; P <.0001)。十三名(39%)患有蛋白质丢失性肠病。和

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