Cardiovascular Research is celebrating its fortieth year of existence this year. Therefore, the Editorial Team would like to take this opportunity to reflect on the Journal's past, present, and future. To look into the past we've invited an author (John Ross Jr.) of the very first CVR paper ever published to give his impressions of basic cardiology at the time of the Journal's inception in 1967. We've also invited editorials from several former editors-in-chief (Peter Sleight, David Hearse, and Michiel Janse) in which they reminisce about their experiences at the helm of the Journal. To look at the present, we have just learned as this editorial goes to press that our impact factor has risen once again, to its highest value ever: 5.826 for the year 2006 (see Fig. 1). This is a very nice "birthday present" to our journal and makes us confident for the years to come.
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