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The interpretation and utility of bone mineral density by dual energy X-ray absorptiometry in chronic kidney disease

机译:双能X线骨密度仪在慢性肾脏病中对骨矿物质密度的解释和应用

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Drugs contributing to overdose deaths are listed on death certificates, but their validity is rarely studied. To assess the accuracy of "morphine" and "codeine" listings on death certificates for unintentional overdose deaths in Allegheny County, PA, investigative and laboratory reports were reviewed. Deaths were reclassified as heroin-related if documentation showed 6-monoacetylmorphine in blood or urine, "stamp bags" or drug paraphernalia at scene, history of heroin use, or track marks. Deaths were considered morphine-related if notes indicated morphine use, prescription, or morphine at scene, or codeine-related if the codeine blood level exceeded morphine. Of 112 deaths with morphine but not heroin listed on the death certificate, 74 met heroin criteria and 21 morphine criteria. Of 20 deaths with both morphine and heroin listed, only one met morphine criteria. Of 34 deaths with codeine listed, only five were attributed to codeine. Consideration of patient history, death scene evidence, and expanded toxicology testing may improve the accuracy of death certificate drug listings.
机译:导致死亡的药物过量已列在死亡证明中,但很少研究其有效性。为了评估宾夕法尼亚州阿勒格尼县因意外过量死亡而在死亡证明上列出的“吗啡”和“可待因”清单的准确性,并审查了调查和实验室报告。如果文件显示现场有血液或尿液,“邮票袋”或吸毒用具,海洛因使用史或痕迹中含有6-一乙酰吗啡,则将死亡重新分类为与海洛因有关。如果笔记表明现场使用吗啡,处方或吗啡,则认为死亡与吗啡有关;如果可待因的血药浓度超过吗啡,则认为死亡与吗啡有关。在死亡证明中列出的112例死于吗啡但没有海洛因的死亡中,有74例符合海洛因标准和21项吗啡标准。在列出了吗啡和海洛因的20例死亡中,只有一个符合吗啡标准。在列出可待因的34例死亡中,只有5例归因于可待因。考虑患者病史,死亡现场证据和扩大的毒理学检测可以提高死亡证明药物清单的准确性。

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