Plenum 1: Hygiene, Umwelt- und Praventivmedizin

摘要

The atopic diseases such as atopic dermatitis, allergic rhinitis and allergic asthma but also severe reactions because e.g. food allergy are increasing. Up to now about 50% of 6 years old children are at least sensitized against atopic allergens. Typically the diseases of this syndrome or the atopic march starts with atopic dermatitis followed by rhinitis and/or asthma. Recent genetic and environmental research results suggest that this is caused by a defect of the barrier function of the skin which increased the likelihood of sensitization. Therefore the maintenance of skin barrier function becomes a major part in the prevention of these diseases. The possibility of prevention is given because skin barrier damage is not only the result of genetic differences but also of environmental influences.