Multifunctional PEG-grafted chitosan copolymer possessing amino and carboxyl (or formyl) groups

摘要

New multifunctional PEG-grafted chitosan copolymers possessing both amino and carboxyl (4) or formyl (5) groups weresynthesized by the grafting reaction method between chitosan and heterobifunctional PEG from anionic polymerization of ethyleneoxide. Completion of the reactions and characterization of the resulting polymers were demonstrated by 1H NMR, FT-IR and GPC studies. The multifunctional polymers may have potential utility in gene/drug co-delivery or heterogeneous catalysis.