Dangers of switching anti-hypertension medication: Focus on 2010 South African Heart Congress.

摘要

Physicians should discourage switching between anti-hypertension medications and should encourage both the patient and the funder to stick with the successfully up-titrated medication. 'There is always the concern that by switching drugs, normally tolerated confidence intervals of bioequivalence studies may be compounded and result in poor blood pressure control and increased risk of suffering a cardiovascular or cere-brovascular event in at-risk patients.' This view was presented in a very considered manner by Prof Peter Meredith, reader in clinical pharmacology at the University of Glasgow, who attended and spoke at the recent SA Heart Congress at Sun City.