Structure of large dsDNA virusesd> Thomas Klose, Department of Biological Sciences, Purdue University, West Lafayette, IN 47907-2032, USA,

摘要

Nucleocytoplasmic large dsDNA viruses (NCLDVs) encompass an ever-increasing group of large eukaryotic viruses, infecting a wide variety of organisms. The set of core genes shared by all these viruses includes a major capsid protein with a double jelly-roll fold forming an icosahedral capsid, which surrounds a double layer membrane that contains the viral genome. Furthermore, some of these viruses, such as the members of the Mimi-viridae and Phycodnaviridae have a unique vertex that is used during infection to transport DNA into the host.