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Efficacy of simultaneous vaccination with Enterisol Ileitis and Ingelvac CircoFLEX in a Swiss breeding farm

机译:在瑞士的一个饲养场中同时接种肠溶性回肠炎和Ingelvac CircoFLEX疫苗的功效

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This study explores administration of two piglet vaccines as compared to the mono- and adjuvant-application. A vaccine against the Porcine Circovirus Type 2 (PCV2) cap protein subunit and a vaccine with attenuated live culture against Lawsonia (L.) intracel-lularis were applied to piglets aged 23.5 days on average. 1'405 animals were divided randomly into four groups. One piglet group was immunized with both vaccines while two other groups were immunized with a combination of one vaccine and adjuvants of alternate vaccination protocol and vice versa. These piglet groups were also compared to a control group supplemented with both adjuvants only. During fattening, pigs, which were simultaneously immunized with Enterisol Ileitis and Ingelvac CircoFLEXvaccine, gained significantly more weight (792 gvday) when compared to piglet groups mono-vaccinated with Ingelvac CircoFLEX (772 g/day) or either with Enterisol Ileitis (774 g/day). Moreover, immunized piglet groups showed significantly higher daily weight gain when compared to adjuvants only inoculated control group (751 gvday). Additionally, during fattening the control group displayed higher mortality (6,3 %) than the three vaccinated groups (Ingelvac CircoFLEX 2,5%, Enterisol? Ileitis 2,3% and thecombination of both vaccines 1,1%). These data imply that simultaneous immunization with PCV2- and L. intracellu-laris specific vaccines positively benefit piglet growth observed by an additive effect on growth parameters in farms harboring both pathogens. Return of investment was calculated of 2.10 on the additional Enterisol? Ileitis vaccination.
机译:与单药和佐剂相比,本研究探索了两种小猪疫苗的施用。平均在23.5天龄的仔猪上接种了2型猪圆环病毒(PCV2)帽蛋白亚基疫苗和减毒活细胞培养法。将1'405只动物随机分为四组。一个仔猪组用两种疫苗免疫,而另外两个组用一种疫苗和其他疫苗接种方案的佐剂组合免疫,反之亦然。还将这些仔猪组与仅添加了两种佐剂的对照组进行了比较。在育肥过程中,与分别接受Ingelvac CircoFLEX(772 g /天)或接受Enterisol回肠炎(774 g /天)。此外,与仅接种佐剂的对照组(751 gvday)相比,免疫仔猪的日增重明显更高。此外,在育肥过程中,对照组的死亡率(6.3%)高于三个接种组(Ingelvac CircoFLEX 2.5%,肠溶性回肠炎2.3%和两种疫苗的组合1.1%)。这些数据表明,通过对两种病原体的农场的生长参数产生累加效应,用PCV2和胞内劳森氏菌特异性疫苗同时免疫可对仔猪的生长产生积极影响。计算出的额外Enterisol的投资回报率为2.10?回肠炎疫苗接种。

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