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Echinacea powder: Treatment for canine chronic and seasonal upper respiratory tract infections

机译:紫锥菊粉:犬慢性和季节性上呼吸道感染的治疗

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摘要

An open multi-centered veterinary clinical trial, comparing conditions before and after treatment with a herbal preparation, containing the powdered root of Echinacea purpurea, was conducted by 6 practicing veterinarians in Switzerland. The plant-based immune stimulant was administered to 41 dogs with manifestations of chronic and seasonal upper respiratory tract infections, including pharyngitis/tonsillitis, bronchitis and kennel cough. Each animal was at an individual stage of the disease, with various symptoms and different severity scores, at start of treatment. There was no control group. Echinacea powder (1:3) was administered with the food at a dose of 1.0 g/10 kg body weight once daily for 8 weeks. Overall efficacy showed significant improvement for 92% of 39 dogs after 4 weeks of treatment and this was confirmed after 8 weeks. Significant reductions of severity and resolution of typical clinical symptoms, of clear nasal secretions, enlargement of lymph nodes, dry cough, dyspnea and dry lung sounds, were evident after 4 weeks. Only two adverse effects, not suspected to be attributable to the study drug, were recorded. Because quality and stability of the Echinacea powder were defined, using an analytical standard and purity tests, thesedata suggest, that the Echinacea preparation can be recommended as a well tolerated alternative treatment of canine upper respiratory tract infections.
机译:瑞士的6名执业兽医进行了一项开放式多中心兽医临床试验,比较了含有紫锥菊粉粉根的草药制剂治疗前后的状况。对41只具有慢性和季节性上呼吸道感染表现的狗(包括咽炎/扁桃体炎,支气管炎和狗窝咳嗽)施以植物性免疫刺激剂。在治疗开始时,每只动物处于疾病的各个阶段,具有各种症状和不同的严重程度评分。没有对照组。将紫锥菊粉(1:3)与食物一起以1.0 g / 10 kg体重的剂量给药,每天一次,持续8周。治疗4周后,总功效显示39只狗中的92%有明显改善,这在8周后得到证实。 4周后,明显减轻了典型临床症状的严重程度和症状,明显的鼻腔分泌物,淋巴结肿大,干咳,呼吸困难和干肺音减轻。仅记录了两种可能不会归因于研究药物的不良反应。由于使用分析标准品和纯度测试确定了紫锥菊粉末的质量和稳定性,这些数据表明,紫锥菊制剂可作为耐受性良好的犬上呼吸道感染的替代治疗方法被推荐。

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