首页> 外文期刊>Scandinavian journal of plastic and reconstructive surgery and hand surgery >Microcirculation in single and multiple-based perforator flaps in an experimental model of rats.
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Microcirculation in single and multiple-based perforator flaps in an experimental model of rats.

机译:大鼠实验模型中单孔和多孔穿孔皮瓣中的微循环。

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Our aim was to evaluate the effect of single and multiple-based perforator flaps on the microcirculation in rats. Two symmetrical abdominal flaps were raised around the midline in 17 rats, and sutured into their original positions after dissection. All major perforators in the flap were left intact on one side, and on the opposite side only one perforator was retained. The microcirculation in the flaps was measured with laser Doppler perfusion imaging at different time intervals. Before dissection of the flap the mean (SD) microcirculation was 5.5 (1.6) units in the multiple-based perforator flap and 5.5 (1.4) in the single-based perforator flap. Within the first two hours after the flap had been raised the highest microcirculation was found after 30 minutes with 7.3 (1.3) units in the multiple-based perforator flap compared with 6.5 (1.4) units in the single-based perforator flap (p = 0.002). We conclude that the microcirculation in the single-based perforator flap was not reduced after dissection. However, a reactive hyperaemic response was found only in the multiple-based perforator flap.
机译:我们的目的是评估单孔和多孔穿孔皮瓣对大鼠微循环的影响。在17只大鼠的中线周围举起两个对称的腹部皮瓣,并在解剖后将其缝合到其原始位置。皮瓣中的所有主要穿孔器在一侧均完好无损,而在另一侧仅保留了一个穿孔器。用激光多普勒灌注成像在不同的时间间隔测量皮瓣中的微循环。在剥离皮瓣之前,多基穿孔皮瓣的平均(SD)微循环为5.5(1.6)单位,单基穿孔皮瓣的平均微循环为5.5(1.4)。在皮瓣升起后的前两个小时内,在30分钟后发现最高的微循环,在多基穿孔皮瓣中为7.3(1.3)单位,而在单基穿孔皮瓣中为6.5(1.4)单位(p = 0.002 )。我们得出的结论是,解剖后单根穿孔皮瓣中的微循环并没有减少。然而,仅在基于多个的穿孔器瓣中发现反应性高氧反应。

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