Synthesis of 1,4-benzodiazepinones and 1,4- benzoxazepinones via palladium-catalyzed amino and oxyacetoxylation

摘要

Palladium-catalyzed amino and oxyacetoxylation have been developed to furnish 1,4-benzodiazepinones and 1,4-benzoxazepinones through the diheterofunctionalization of alkenes. This study demonstrates the ability of this new methodology to allow 7-exo ring-closure