Separation of thaiamine mononitrate ascorbic acid calcium-D-pantothenate, Niacinamide. pyridoxine hydrochloride and riboflavin by using propyl hydroxy β-cyclodextrin as an ion-pairing reagent

摘要

The present communication dipics the development of a reversed phase H.P.L C. for the simultaneous estimation of acidic and basic vitamins from solid dosage of polyvitamin and vitamin -B-complex tablets of therapeutic and prophylactic N.F.l.The separation of vitamins was determined at 280nm.The proposed method is advantageous over reported method, the introduction of propyl hydroxy β-cyclodextrin as an ion-pairing reagent used and found to be profound effect over other ion-pairing reagent. The proposed methods are linear accurate and precise and applicable for daily quality control routine analysis