Application of UV-spectrophotometry and first order derivative methods for determination of Teimisartan in bulk and tablets

摘要

Two simple,rapid,sensitive and accurate'UV-spectrophotometry'and'first order derivative'methods have been developed for estimation of teimisartan in bulk and tablets.0.1M NaOH was used as solvent.In,'UV-spectrophotometry method'absorbance of the samples was recorded at 295 nm.In'first order derivative method',the amplitude of the troughs was recorded at 311 nm.In both the methods,teimisartan follows linearity in concentration range 2-18 mu g/ml.In both the methods,assay results were in good agreement with label claim.These methods were validated statistically and recovery studies.