Tricarbonyl[(1-4-eta)-2-methoxy-5-methylenecyclohexa-1,3-diene]iron as a synthetic intermediate: Sequential electrophilic and nucleophilic additions

摘要

Tricarbonyl[(1-4-eta)-2-methoxy-5-methylene-cyclohexa-1,3-diene]iron reacts with electrophiles to give the cyclohexadienylium-Fe(CO)(3) cation, which either reacts with nucleophiles to form a new quaternary center or undergoes competitive loss of an acidic alpha-proton to give a new triene complex. This constitutes a new reaction sequence for the synthesis of 4,4-disubstituted cyclohexen-2-ones with the simultaneous introduction of two functional groups. [References: 12]