Radical Cyclization Cascade Involving Ynamides: An Original Access to Nitrogen-Containing Heterocycles

摘要

A radical cascade involving a 5-exo-dig cyclization followed by a 6-endo-trig radical trapping transforms ynamides into heterogeneous polycyclic compounds in good yields. This leads interestingly to the formation of isoindols, isoindolinones, and pyridoisoindolones.