Palladium (II)-Catalyzed Tandem Reaction of Intramolecular Aminopalladation of Allenyl N-Tosylcarbamates and Conjugate Addition

摘要

A divalent palladium-catalyzed tandem cyclization-coupling reaction of allenyl N-tosylcarbamates and acrolein was developed. The reaction gave aldehyde-functionalized 2-oxazolidinones in one step with high regioselectivity. A mechanism involving intramolecular aminopalladation of allene, followed by insertion of alkene and C-Pd bond protonolysis, is proposed.