A New Method for Translating the Asymmetric Ni/Cr-Mediated Coupling Reactions from Stoichiometric to Catalytic

摘要

A new method has been developed for effectively translating the degree of asymmetric induction and the chemical yield achieved in the Stoichiometric asymmetric Ni/Cr-mediated coupling to a catalytic asymmetric process via a chiral sulfonamide ligand.It has also been shown that the Ni catalyst plays a central role.Among a number of the Ni catalysts,the 2,9-dimethylphenanthroline/NiCI_2 complex(7)has been found to be the most effective.