Synthesis and characterization of the new type of tetrazolescontaining barbiturates

摘要

Reaction of 4-cyano benzaldehyde with sodium azide in presence of ammonium Chloride in dimethyl formamide under reflux conditions gave 4-(1H-tetrazole-5-yl)benzaldehyde, which was condense with barbiturates under knoevenagel condensations to give new substituted derivatives of tetrazoles with good yield.