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Morphometrical study of minor salivary gland in xerostomic patients with altered lipid metabolism

机译:口干症患者脂质代谢改变的小唾液腺的形态计量学研究

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摘要

OBJECTIVE: To evaluate the correlation between dysli-pidemia in patients with oral dryness and the development of non-specific histopathological findings in their labial salivary gland biopsies.METHODS: Thirty seven patients suffering from oral dryness (18 patients with dyslipidemia and 19 age-matched patients with normal lipid blood levels) underwent labial salivary gland biopsy. Total acinar area (TAA), acinar cell number, acinar lumen area (ALA), duct lumen area (DLA), area occupied by cells in acinus (AoCA), and area of one acinar cell (OAC) were calculated.RESULTS: A significantly (P < 0.05) increased AoCA, OAC, and DLA in labial glands from patients with impaired lipid metabolism, compared to controls, were found.CONCLUSION: A positive relationship between dyslipidemia and morphological changes in labial salivary glands was obtained.
机译:目的:评估口干症患者的血脂异常与唇唾液腺活检组织中非特异性组织病理学发现之间的相关性。方法:三十七例口干症患者(18例血脂异常和19岁年龄相匹配的患者)血脂水平正常的患者进行唇唾液腺活检。计算总腺泡面积(TAA),腺泡细胞数量,腺泡内腔面积(ALA),导管内腔面积(DLA),腺泡内细胞占据的面积(AoCA)和一个腺泡细胞的面积(OAC)。与对照组相比,脂代谢受损患者的唇腺中的AoCA,OAC和DLA显着增加(P <0.05)。结论:血脂异常与唇唾液腺的形态变化呈正相关。

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