Letter to the editor: Obesity and inflammation: Change in adiponectin, C-reactive protein, tumour necrosis factor-alpha and interleukin-6 after bariatric surgery

摘要

I have read with great interest the recent article by Illan-Gomez et al. describing their analysis of inflammation markers before and after bariatric surgery [1]. I was hoping that the research would add to the discussion of the role of inflammation in obesity previously described by others [2-4]. However, the statistical tests chosen to analyze the data do not on their face address the specific characteristics of the data set in two important ways: first, t tests are used rather than analysis of variance for repeated measures, and second, the data, while not normally distributed, are analyzed with tests that assume a normal distribution. Further, the authors did not explain and defend the choices they made. Thus, the results and conclusions cannot be accepted as presented.