Patterns of systemic uptake of 18-FDG with positron emission tomography/computed tomography (PET/CT) studies in patients with presumed ocular tuberculosis

摘要

Aim: To report the patterns and sites of 18-FDG uptake in patients of presumed ocular tuberculosis. Materials and methods: The clinical and investigational findings of 11 patients were reviewed retrospectively. These included 6 males and 5 females with a mean age of 46.2 years. 21 eyes were included in the data analysis. Clinical presentations include 15 eyes with anterior uveitis, 2 eyes with retinal vasculitis, 2 eyes with panuveitis and 2 eyes with multifocal choroidopathy. Results: Two distinct patterns of systemic uptake emerged. Pattern 1: No detectable systemic uptake (4 patients). Pattern 2: Detectable systemic uptake. a. Chest disease only (2 patients). b. Disseminated pattern, uptake seen at multiple sites (4 patients). c. Extrapulmonary only (1 patient). Conclusions: Ocular tuberculosis may often be part of a wider disseminated disease.