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Transgenerational Epigenetic Inheritance: Myths and Mechanisms

机译:跨代表观遗传:神话与机制

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Since the human genome was sequenced, the term "epigenetics" is increasingly being associated with the hope that we are more than just the sum of our genes. Might what we eat, the air we breathe, or even the emotions we feel influence not only our genes but those of descendants? The environment can certainly influence gene expression and can lead to disease, but transgenerational consequences are another matter. Although the inheritance of epigenetic characters can certainly occur—particularly in plants—how much is due to the environment and the extent to which it happens in humans remain unclear.
机译:自从人类基因组被测序以来,“表观遗传学”一词越来越多地与人们希望我们不仅仅是基因的总和有关。我们的饮食,呼吸的空气,甚至我们感觉到的情绪可能不仅影响我们的基因,而且影响后代的基因吗?环境当然可以影响基因表达并可能导致疾病,但跨代后果是另一回事。尽管表观遗传特性的遗传当然可以发生(尤其是在植物中),但是多少是由于环境以及在人类中发生的程度尚不清楚。

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