Thermodynamic Characteristics of Acid-Base Equilibria of DL-alpha-Alanyl-DL-Norleucine in Aqueous Solutions at 298 K

摘要

Protolytic equilibria in aqueous solutions of DL-alpha-alanyl-DL-norleucine are studied via potentiometry and calorimetry. Measurements are made at 298.15 K and ionic strengths of 0.5, 1.0, and 1.5 (against a background of potassium nitrate). The thermodynamic characteristics (pK, Delta G, Delta H, Delta S) of the stepwise dissociation of the dipeptide both in aqueous-salt solutions and in standard solution are obtained for the first time.