Methods of Reconstruction of Spectra in Multidimensional NMR Spectroscopy

摘要

In this review, some methods for speeding up the performance of multidimensional nuclear mag- netic resonance (NMR) experiments are discussed. It is shown that, at a sufficiently high spectral sensitivity, which does not require multiple scanning with averaging, two-dimensional proton-correlation experiments (COSY and TOCSY) can be performed in less than one minute. A multifold decrease in the time of multidi- mensional experiments can be achieved by various methods, for example, by the direct excitation of reso- nance signals with a set of different frequencies obtained using the Hadamard matrix. Methods for recon- structing multidimensional NMR spectra based on the inverse Radon transform and a number of other prom- ising methods are also considered.