Synthesis of 6,8-Substituted 4-(Hydroxyphenylamino)-and 4-(Aminophenylamino)-2-methylquinolines

A. A. Avetisyan; I. L. Aleksanyan; L. P. Ambartsumyan

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Synthesis of 6,8-Substituted 4-(Hydroxyphenylamino)-and 4-(Aminophenylamino)-2-methylquinolines

机译：6,8-取代的4-（羟基苯基氨基）-和4-（氨基苯基氨基）-2-甲基喹啉的合成

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摘要

A procedure has been developed for the synthesis of 4-(hydroxyphenylamino)- and 4-(amino-phenylamino)-2-methylquinolines having a substituent in the 6(8)-position of the quinoline ring from the corresponding 4-chloro-2-methylquinolines and o-, m-, and p-aminophenols and o-, m-, and p-phenylenediamines.

机译：已经开发了一种用于从相应的4-氯代2合成在喹啉环的6（8）-位具有取代基的4-（羟基苯基氨基）-和4-（氨基-苯基氨基）-2-甲基喹啉的方法-甲基喹啉和邻，间和对氨基苯酚以及邻，间和对苯二胺。

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《Russian Journal of Organic Chemistry》 |2007年第7期|共4页
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A. A. Avetisyan; I. L. Aleksanyan; L. P. Ambartsumyan;
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中图分类有机化学;
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1. Synthesis of 6,8-Substituted 4-(Hydroxyphenylamino)-and 4-(Aminophenylamino)-2-methylquinolines [J] . A. A. Avetisyan, I. L. Aleksanyan, L. P. Ambartsumyan Russian Journal of Organic Chemistry . 2007,第7期

机译：6,8-取代的4-（羟基苯基氨基）-和4-（氨基苯基氨基）-2-甲基喹啉的合成
2. Design, synthesis and anticonvulsant activities of novel 1-(substituted/unsubstituted benzylidene)-4-(4-(6,8-dibromo-2-(methyl/phenyl)-4- oxoquinazolin-3(4H)-yl)phenyl) semicarbazide derivatives [J] . SaravananG., AlagarsamyV., PrakashC.R. Bioorganic and Medicinal Chemistry Letters . 2012,第9期

机译：新型1-（取代/未取代的苄基）-4-（4-（6,8-二溴-2-（甲基/苯基）-4-氧代喹唑啉-3（4h） - yl）苯基）的设计，合成和抗惊厥活性氨基脲衍生物
3. Synthesis and spectral studies of biologically active organophosphorus derivatives of substituted 4-(2-hydroxyphenylamino)-2H-chromen-2-one [J] . Zghab Imen, Trimeche Belsem, Besbes Malek, Medicinal chemistry research: an international journal for rapid communications on design and mechanisms of action of biologically active agents . 2015,第5期

机译：取代的4-（2-羟基苯基氨基）-2H-铬-2--2-生物活性有机磷衍生物的合成和光谱研究
4. Synthesis of 4-(4-alkylphenyl)-4'-amino-α-methyl-stilbene,4-(4-alkylphenyl)-4'-isothiocyanato-α-methylstilbene, and 4-(4-alkylphenyl)-4'-cyano-α-methylstilbene liquid crystals [C] . C.S. Hsu, C.Y. Chang International Display Manufacturing Conference FPD Expo(IDMC'03) . 2003

机译：4-（4-烷基苯基）-4'-氨基-α-甲基-，4-（4-烷基苯基）-4'-异硫氰酸根合-α-甲基sti和4-（4-烷基苯基）-4'-的合成氰基-α-甲基sti液晶
5. Studies on multicomponent reactions: New 4- and 5-component routes to aminoacid diamides and 3-component routes to substituted indoles by modification of the classical Ugi and Fischer indole reactions. [D] . Simoneau, Christopher Allen. 2007

机译：多组分反应的研究：通过改良经典的Ugi和Fischer吲哚反应，新的4和5组分途径可生成氨基酸二酰胺，而3组分途径可生成取代的吲哚。
6. Synthesis Binding Affinity Radiolabeling and MicroPET Evaluation of 4-(2-Substituted-4-substituted)-8-(dialkylamino)-6-methyl-1-substituted-34-dihydropyrido23-bpyrazin-2(1H)-ones as Ligands for Brain Corticotropin-Releasing Factor Type-1 (CRF1) Receptors [O] . Jeffrey S. Stehouwer, Chase H. Bourke, Michael J. Owens, -1

机译：4-（2-取代-4-取代）-8-（二烷基氨基）-6-甲基-1-取代-34-二氢吡啶并23-b吡嗪的合成结合亲和力放射性标记和MicroPET评价-2（1H）-ones作为大脑促肾上腺皮质激素释放因子1型（CRF1）受体的配体
7. Design and Synthesis of Novel N-(4-(Pyridin-2-yloxy)benzylidene)-4- 4-(substituted)phenylsemicarbazides as Potential Anticonvulsant Agents [O] . Prem Singh, Laxmi Tripathi 2018

机译：新的N-（4-（吡啶-2-基氧基）苄基）-4- 4-（取代）苯基氨基脲作为潜在的抗惊厥药剂的设计和合成

Synthesis of 6,8-Substituted 4-(Hydroxyphenylamino)-and 4-(Aminophenylamino)-2-methylquinolines

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