Characteristic Features of Reduction with i-BU2AlH of Products of Ring Opening with (-)-α-Metnylbenzylamine of (3aS,4R,7R,7aS)-3a,4,7,7a-Tetrahydro-4,7-epoxy-2-benzofuran-1,3-dione

摘要

A special procedure of synthesis was developed for amidoaminals of atypical topology through a reduction with i-Bu2AlH of primary products of thermodynamical opening of (3aS,4R,7R,7aS)-3a,4,7,7a-tetrahydro-4,7-epoxy-2-benzofuran-1,3-dione at treating with (-)-α-methylbenzylamine. Characteristic spectral criteria are described for assignment of diastereomeric compounds; possible routes of reaction stages are considered.