首页> 外文期刊>Obstetrics and Gynecology: Journal of the American College of Obstetricians and Gynecologists >Positive interferon-gamma release assay leading to a diagnosis of mycobacterium tuberculosis pericarditis in pregnancy
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Positive interferon-gamma release assay leading to a diagnosis of mycobacterium tuberculosis pericarditis in pregnancy

机译:干扰素-γ释放阳性试验可导致妊娠分枝杆菌心包炎的诊断

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BACKGROUND: Tuberculosis during pregnancy is associated with increased complications. The wide range of presentations among patients with extrapulmonary tuberculosis can make diagnosis and treatment difficult. CASE: We present the case of a patient with Mycobacterium tuberculosis pericarditis presenting in pregnancy with recurrent pericardial effusions. The diagnosis of active tuberculosis was made and treatment initiated after a positive interferon-gamma release assay and granulomatous pericardial pathology despite negative tuberculin skin testing. Culture of pericardial tissue obtained by pericardectomy confirmed the diagnosis 1 month after initiation of treatment. CONCLUSION: This case report demonstrates the use of interferon-gamma release assay in diagnosing tuberculosis among high-risk pregnant patients. Although limited by expense and minimal experience in pregnancy, these assays may be useful to screen for tuberculosis in high-risk pregnant populations.
机译:背景:妊娠期结核病与并发症增加有关。肺外结核患者的广泛表现可能使诊断和治疗变得困难。病例:我们介绍了一名孕妇结核分枝杆菌性心包炎,反复心包积液。尽管结核菌素皮肤试验阴性,但在阳性干扰素-γ释放测定和肉芽肿性心包病理检查之后,进行了活动性结核的诊断并开始治疗。心包切除术获得的心包组织培养证实了开始治疗后1个月的诊断。结论:该病例报告证明了干扰素-γ释放测定法在高危孕妇中诊断结核的应用。尽管受费用和怀孕经验的限制,但这些检测方法可能对筛查高危孕妇人群的结核病有用。

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