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We thank Danhof et al for their interest in our work and welcome the opportunity to clarify our methodology. First, we excluded four of the studies after diligent review against explicit inclusion and exclusion criteria. The studies by Albrechtsen et al and Kristensen et al were excluded because we were unable to isolate the data of women who had loop electrosurgical excision procedure (LEEP) from other cervical excision procedures, which would not answer our question of the association between LEEP and preterm birth. Further, we excluded the studies by Jakobsson et al and Bruinsma et al because they included women with cervical cancer, in whom treatment and outcomes are clearly different from patients with dysplasia only. Finally, the study by Ortoft et al6 was, in fact, included in our meta-analysis.
机译:我们感谢Danhof等人对我们的工作感兴趣,并欢迎有机会阐明我们的方法。首先,我们在针对明确的纳入和排除标准进行了认真审查后,排除了四项研究。 Albrechtsen等人和Kristensen等人的研究被排除在外,因为我们无法从其他宫颈切除术中分离出进行环行电外科切除术(LEEP)的女性的数据,这无法回答我们关于LEEP与早产之间的关系出生。此外,我们排除了Jakobsson等人和Bruinsma等人的研究,因为它们包括患有宫颈癌的妇女,在这些妇女中,治疗和结局与仅发育不良的患者明显不同。最后,Ortoft等[6]的研究实际上包含在我们的荟萃分析中。

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