Oophorectomy and Hysterectomy and Cancer Incidence in the Cancer Prevention Study-ll Nutrition Cohort

摘要

We read with attention the interesting article by Gaudet et al. The authors present research that suggests an inverse association between the execution of hysterectomy plus bilateral salpingo-oophorectomy and the risk of developing cancer in woman aged 55 years or younger. In particular, women who underwent hysterectomy (with or without bilateral salpingo-oophorectomy) before age 45 years experienced a lower risk of developing cancer in comparison with women who had not undergone surgery. Despite the undoubted importance of these findings, some points of the present research have to be addressed to overcome concerns and reduce the rate of unnecessary procedures. In fact, we believe that the potential reduction of the cancer rate does not justify uterine and adnexal removal if another clinical indication does not exist.