Reaction of(Chloromethyl)phenoxyphosphinothioyl Isothiocyanate with 2-(Methylamino)ethylphosphonates

摘要

Recently we showed that addition of diphenyl a-(methylamino)benzylphosphonate to phenyl iso-cyanate or phenyl isothiocyanate proceeds easily in the presence of a catalytic quantity of triethylamine with formation of N,N'-substituted heterocycles,viz.diastereomeric 1,3,4-diazaphospholidines.We found that the reaction of O-phenyl(chloromethyl)-phosphonoisothiocyanatidothioate(I)with p-amino-alkylphosphonates provides a different synthetic result.