Reactions of Zinc Enolates Derived from 1-Aryl-2-bromo-2-phenylethanone and 2-Bromoindan-1-one with Alkyl 2-Oxochromene-and 6-Bromo-2-oxochromene-3-carboxylates

摘要

Zinc enolates derived from 1-aryl-2-bromo-2-phenylethanone react with alkyl 2-oxochromene-3-carboxylates and methyl 6-bromo-2-oxochromene-3-carboxylate to give,respectively,alkyl 4-(2-aryl-2-oxo-1-phenylethyl)-2-oxochroman-3-carboxylates and methyl 6-bromo-4-(2-aryl-2-oxo-1-phenylethyl)-2-oxo-chroman-3-carboxylate as a single stereoisomer.Zinc enolates derived from 2-bromoindan-1-one react with alkyl 2-oxochromene-3-carboxylates to give alkyl 2-oxo-4-(1-oxoindan-2-yl)chroman-3-carboxylates as a single stereoisomer.