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New Ce(III) Complex Compounds of 2-(N,N- dimethylbiguanidil)-penta-1,5-dioic Acid with Biological Activity

机译:具有生物活性的2-(N,N-二甲基双胍基)-penta-1,5-二甲酸新的Ce(III)络合物

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摘要

The paper present the biological properties, total antioxidant capacity and antimicrobial activity against different Gram positive and Gram negative strains and fungi, of some new Ce(III) complex compounds with Schiff base as ligands; the ligands were obtained by condensation between a-ketoglutaric acid and N,N-dimethylbiguanide (base and hydrochloride), in well-established condition. The new synthesized ligands were obtained as hydrochloride salt (2-(N,N-dimethylbiguanidyl)-penta-1,5-dioic hydrochloride acid, V) and also in neutral form (2-(N,N-dimethylbiguanidyt)-penta 1,5-dioic acid, V); the new ligands and theirs Ce(III) complex compounds have been physico-chemically characterized by elemental chemical analysis, molar electrical conductivity, FT/IR, UV-Vis spectrometry and NMR.
机译:本文介绍了一些以席夫碱为配体的新型Ce(III)配合物对不同革兰氏阳性和革兰氏阴性菌株和真菌的生物学特性,总抗氧化能力和抗菌活性。所述配体是在充分确定的条件下,通过α-酮戊二酸与N,N-二甲基双胍(碱和盐酸盐)之间的缩合而获得的。获得了新的合成配体,为盐酸盐(2-(N,N-二甲基双胍基)-戊-1,5-二酸盐酸盐,V),也呈中性形式(2-(N,N-二甲基双胍基)-戊1 ,5-二甲酸,V);通过分子化学分析,摩尔电导率,FT / IR,UV-Vis光谱和NMR对新的配体及其Ce(III)配合物进行了物理化学表征。

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