Synthesis of 4-alkyl-3,4-dihydronaphtho[2,3-f] quinoxaline- 2,7,12-(1H)-triones and 3-alkyl-5-arylamino-2-chloromethyl- 3H-anthra[1,2-d]imidazole-6,ll-diones based on reactions of 1-amino-9,10-anthraquinones with chloroacetyl chloride

摘要

A method was developed for the synthesis of 4-alkyl-3,4-dihydronaphtho[2,3-f]quinoxaline-2,7,12-(1H)-triones starting from 1-chloroacetylamino-2-halo-9,10-anthraquinones and primary and secondary amines. The reactions of 1-amino-2-alkylamino-9,10-anthraquinones with chloroacetyl chloride afforded 3-alkyl-5-arylammo-2-chloromethyl-3H-anthra[1,2-d]-imidazole-6,11-diones. The reaction products contain chloroalkyl groups, which can undergo further modifications.