...
首页> 外文期刊>Respiration: International Review of Thoracic Diseases >The Usefulness of Inspiratory Flow Rate during Inhalation Corticosteroid Therapy in Asthma.
【24h】

The Usefulness of Inspiratory Flow Rate during Inhalation Corticosteroid Therapy in Asthma.

机译:吸入性糖皮质激素治疗哮喘期间吸气流速的有用性。

获取原文
获取原文并翻译 | 示例
           

摘要

Background: The recently released handheld In-Check device can be used to measure the peak inspiratory flow rate (PIF) of patients and is reportedly useful in determining whether the PIF is sufficient for using inhaler devices. In this study, we evaluated the effects of instructions for the use of the device and of the device type based on measurements of the PIF in asthma. Objectives: One hundred and thirty-five asthmatic patients who used a fluticasone propionate Diskus (FP-DK) or a budesonide Turbuhaler (BUD-TH) were studied. Methods: The PIF was measured by the In-Check device. For patients without a sufficient PIF of 50 l/min, instructions for the use of the device were given, and the device was changed to hydrofluoroalkan-beclomethasone dipropionate (HFA-BDP). Results: A significant correlation between the PIF and peak expiratory flow rate (p < 0.0001) was found. In 10 patients in whom the PIF did not increase to >50 l/min after instructions, the device was changed to HFA-BDP, which resulted in significant improvements in lung function in terms of the forced expiratory volume in 1 s (p = 0.018), peak expiratory flow (p = 0.038) and the maximum expiratory flow rates at 50% (p = 0.018) and 25% (p = 0.011). Conclusions: Measurement of the PIF by the In-Check device is useful in the clinical management of asthma, to provide an appropriate device so as to improve lung function.
机译:背景:最近发布的手持式In-Check设备可用于测量患者的峰值吸气流速(PIF),据报道可用于确定PIF是否足以使用吸入器设备。在这项研究中,我们根据哮喘患者PIF的测量值评估了使用该设备和使用该设备类型的说明的效果。目的:研究了135例使用丙酸氟替卡松(FP-DK)或布地奈德Turbuhaler(BUD-TH)的哮喘患者。方法:通过In-Check设备测量PIF。对于没有足够的PIF 50 l / min的患者,给出了使用该设备的说明,并将该设备更改为氢氟烷-倍氯米松二丙酸酯(HFA-BDP)。结果:发现PIF与呼气峰值流速之间存在显着相关性(p <0.0001)。在10名患者的PIF值在指令后未增加至> 50 l / min的患者中,将设备更换为HFA-BDP,这在1 s的强制呼气量方面显着改善了肺功能(p = 0.018) ),最大呼气流量(p = 0.038)和最大呼气流量分别为50%(p = 0.018)和25%(p = 0.011)。结论:In-Check设备对PIF的测量可用于哮喘的临床治疗,为改善肺功能提供合适的设备。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号