A randomized trial assessing the impact of three different glycoprotein IIb/IIIa antagonists on glycoprotein IIb/IIIa platelet receptor inhibition and clinical endpoints in patients with acute coronary syndromes

Holmes Lewis E.; Gupta Rohan; Rajendran Saissan; Luu John; French John K.; Juergens Craig P.

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A randomized trial assessing the impact of three different glycoprotein IIb/IIIa antagonists on glycoprotein IIb/IIIa platelet receptor inhibition and clinical endpoints in patients with acute coronary syndromes

机译：评估三种不同糖蛋白IIb / IIIa拮抗剂对急性冠状动脉综合征患者糖蛋白IIb / IIIa血小板受体抑制作用和临床终点的影响的随机试验

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AimsTo compare three glycoprotein IIb/IIIa receptor antagonists (GPIs) in terms of platelet inhibition and major adverse cardiac events (MACEs), and assess the rate of bleeding and MACEs between GPIs and coadministered P2Y12 agents.

机译：目的比较三种糖蛋白IIb / IIIa受体拮抗剂（GPI）的血小板抑制作用和主要不良心脏事件（MACE），并评估GPI和共同给药的P2Y12药物之间的出血率和MACE。

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《Cardiovascular therapeutics》 |2016年第5期|共7页
作者
Holmes Lewis E.; Gupta Rohan; Rajendran Saissan; Luu John; French John K.; Juergens Craig P.;
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正文语种 eng
中图分类心脏、血管（循环系）疾病;
关键词
Abciximab; Acute coronary syndrome; Eptifibatide; Glycoprotein IIbIIIa antagonist; Percutaneous coronary intervention; Tirofiban;

机译：阿昔单抗;急性冠脉综合征;依替巴肽;糖蛋白IIbIIIa拮抗剂;经皮冠状动脉介入治疗;替罗非班;

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1. A randomized trial assessing the impact of three different glycoprotein IIb/IIIa antagonists on glycoprotein IIb/IIIa platelet receptor inhibition and clinical endpoints in patients with acute coronary syndromes [J] . Holmes Lewis E., Gupta Rohan, Rajendran Saissan, Cardiovascular therapeutics . 2016,第5期

机译：评估三种不同糖蛋白IIb / IIIa拮抗剂对急性冠状动脉综合征患者糖蛋白IIb / IIIa血小板受体抑制作用和临床终点的影响的随机试验
2. Attenuation of rebound ischemia after discontinuation of heparin therapy by glycoprotein IIb/IIIa inhibition with eptifibatide in patients with acute coronary syndromes: observations from the platelet IIb/IIIa in unstable angina: receptor suppression [J] . Lauer MA, Houghtaling PL, Peterson JG, Circulation: An Official Journal of the American Heart Association . 2001,第23期

机译：糖冠蛋白IIb / IIIa抑制和埃替非巴肽抑制肝素治疗中止后，急性冠脉综合征患者的反弹性缺血减轻：不稳定型心绞痛患者血小板IIb / IIIa的观察：受体抑制
3. Attenuation of rebound ischemia after discontinuation of heparin therapy by glycoprotein IIb/IIIa inhibition with eptifibatide in patients with acute coronary syndromes: observations from the platelet IIb/IIIa in unstable angina: receptor suppression [J] . Lauer MA, Houghtaling PL, Peterson JG, Circulation: An Official Journal of the American Heart Association . 2001,第23期

机译：糖冠蛋白IIb / IIIa抑制和埃替非巴肽抑制肝素治疗中止后，急性冠脉综合征患者的反弹性缺血减轻：不稳定型心绞痛患者血小板IIb / IIIa的观察：受体抑制
4. The Long-Term Clinical Outcomes of Platelet Glycoprotein Ilb/IIIa Inhibitor Combined with Low Molecular Weight Heparin in Patients with Acute Coronary Syndrome [C] . J.H. Kim, M.H. Jeong, Y.J. Hong, International Congress on Thrombosis . 2004

机译：血小板糖蛋白ILB / IIIa抑制剂的长期临床结果与急性冠状动脉综合征患者低分子量肝素联合
5. Platelet adhesion to fibrin(ogen) in an in vitro (re)perfusion model: Effects of rt-PA, c7E3 Fab, and the GP IIb/IIIa receptor Pl(A) polymorphism. [D] . Huang, Trevor Clarence. 2001

机译：在体外（再）灌注模型中血小板对血纤蛋白（原）的粘附：rt-PA，c7E3 Fab和GP IIb / IIIa受体Pl（A）多态性的影响。
6. Use of platelet glycoprotein IIb/IIIa inhibitors in diabetics undergoing PCI for non-ST-segment elevation acute coronary syndromes: impact of clinical status and procedural characteristics [O] . Timm Bauer, Helge Möllmann, Franz Weidinger, -1

机译：血小板糖蛋白IIb / IIIa抑制剂在接受PCI治疗的非ST段抬高的急性冠脉综合征的糖尿病患者中的使用：对临床状况和程序特征的影响
7. The impact of three different glycoprotein platelet receptor IIb/IIIa antagonists on glycoprotein IIb/IIIa platelet receptor inhibition and clinical endpoints in patients with acute coronary syndromes [O] . L. Holmes, R. Gupta, S. Rajendran, 2015

机译：三种不同糖蛋白血小板受体IIB / IIIA拮抗剂对急性冠状动脉综合征患者糖蛋白IIB / IIIa血小板受体抑制和临床终点的影响

A randomized trial assessing the impact of three different glycoprotein IIb/IIIa antagonists on glycoprotein IIb/IIIa platelet receptor inhibition and clinical endpoints in patients with acute coronary syndromes

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