t(8;21) acute myeloid leukemia with trilineage phenotype diagnosed by electron microscopy

摘要

AML-M2 is a common subtype of acute myeloid leukemia (AML), usually associated with transloca-tion t(8;21) and often accompanied by eosinophilia , Bone marrow (BM) basophilia is a rarely encountered finding in this type of AML, and a single case of acute basophilic leukemia (ABL) with t(8;21) was recently reported . Increased number of basophils and eosinophils, and the presence of hybrid eosinophil-basophil granulocytes are well known features in chronic myelogenous leukemia (CML) and AML associated with invl6(pl3q22) .