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首页> 外文期刊>Cardiovascular therapeutics >Resting heart rate does not reflect the degree of beta-blockade in subjects with heart failure on chronic beta-blocker therapy.
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Resting heart rate does not reflect the degree of beta-blockade in subjects with heart failure on chronic beta-blocker therapy.

机译:静息心率不能反映接受慢性β受体阻滞剂治疗的心力衰竭患者的β受体阻滞程度。

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摘要

We investigated the relationship between resting heart rate (HR) and two measures of beta-1 receptor sensitivity/blockade: (1) the percentage of maximal predicted heart rate reached during exercise (%MPHR), and (2) the HR increase per unit of circulating norepinephrine (NE) or the chronotropic responsiveness index (CRI) in 28 patients with systolic CHF on chronic beta-blocker therapy. Our results show that resting HR is not associated with HR response during exercise nor with beta-1 receptor sensitivity to circulating NE.
机译:我们研究了静息心率(HR)与两种测量β-1受体敏感性/阻断措施之间的关系:(1)运动期间达到的最大预测心率百分比(%MPHR),以及(2)单位心率增加慢性β-受体阻滞剂治疗28例收缩期CHF患者的循环去甲肾上腺素(NE)或变时反应性指数(CRI)的变化。我们的结果表明,静息HR与运动期间的HR反应无关,也与β-1受体对循环NE的敏感性无关。

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