Synthesis of Some Novel 5,7-Disubstituted-2-phenyl-5H-[1,3,4]thiacliazolo [3,2-a]pyrimidine Derivatives and Evaluation of Their Biological Activity

摘要

Background: In the present study, a series of 5,7-disubstituted-2-phenyl-5H-[1,3,4] thiadiazolo[3,2-a]pyrimidine derivatives have been reported. The title compounds were synthesized by the reaction of substituted chalcones with 5-phenyl-1,3,4-thiadiazol-2-amine in n-butanol.