Excellent Exo/Endo-Selectivity in the 1,3-dipolar cycloaddition of cyclic azomethine ylide: Exploring the facile investigation of cocaine antagonists

摘要

High exo-selectivity was achieved in the 1,3-dipolar cycloaddition of a cyclic azomethine ylide and phenyl vinyl sulfone or Opplozer's camphorsultam chiral dipolarophile leading to the synthesis of two novel tropane compounds.