Synthesis of novel fused coumarine and naphtho[2,1-b]pyrano[3,2-e][1,2,4] triazolo[1,5-c]pyrimidine derivatives

Sa?d A.B.; Romdhane A.; Elie N.; Touboul D.; Jannet H.B.

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Synthesis of novel fused coumarine and naphtho[2,1-b]pyrano[3,2-e][1,2,4] triazolo[1,5-c]pyrimidine derivatives

机译：新型融合香豆素和萘并[2,1-b]吡喃并[3,2-e] [1,2,4]三唑并[1,5-c]嘧啶衍生物的合成

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New 14-(Aryl)-14H-naphto[2,1-b]pyrano[3,2-e][1,2,4]triazolo[1,5-c] pyrimidine-2-Acetonitriles have been prepared. The chemical behaviour of these compounds was studied towards Knoevenagel condensation with salicylaldelyde derivatives, thus, a series of 2-(coumarin-3″-yl)-14(Aryl)-14H-naphto[2,1- b]pyrano[3,2-e][1,2,4]triazolo[1,5-c]pyrimidines was obtain-ed. Their structures were characterized with IR, ES-HR-MS, 1H NMR and 13C NMR.

机译：制备了新的14-（芳基）-14H-萘并[2,1-b]吡喃并[3,2-e] [1,2,4]三唑并[1,5-c]嘧啶-2-乙腈。研究了这些化合物在水杨醛衍生物与Knoevenagel缩合反应中的化学行为，因此，生成了一系列2-（香豆素-3″-基）-14（芳基）-14H-萘并[2,1-b]吡喃并[3，得到2-e] [1,2,4]三唑并[1,5-c]嘧啶。用IR，ES-HR-MS，1 H NMR和13 C NMR表征它们的结构。

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《Letters in organic chemistry》 |2013年第3期|共6页
作者
Sa?d A.B.; Romdhane A.; Elie N.; Touboul D.; Jannet H.B.;
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正文语种 eng
中图分类有机化学;
关键词
Coumarin-3-yl-pyranotriazolopyrimidines; Knoevenagel condensation; Naphtopyranes; Triazolopyrimidines;

机译：香豆素-3-基-吡喃三唑并嘧啶;Knoevenagel缩合;萘并吡喃并三唑并嘧啶;

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1. Synthesis of novel fused coumarine and naphtho[2,1-b]pyrano[3,2-e][1,2,4] triazolo[1,5-c]pyrimidine derivatives [J] . Sa?d A.B., Romdhane A., Elie N., Letters in organic chemistry . 2013,第3期

机译：新型融合香豆素和萘并[2,1-b]吡喃并[3,2-e] [1,2,4]三唑并[1,5-c]嘧啶衍生物的合成
2. Synthesis and antigenotoxic activity of some naphtho(2,1-b)pyrano(3,2-e)(1,2,4)triazolo(1,5-c)pyrimidine derivatives. [J] . Chabchoub F, Messaad M, Ben-Mansour H, European Journal of Medicinal Chemistry: Chimie Therapeutique . 2007,第5期

机译：某些萘并（2,1-b）吡喃并（3,2-e）（1,2,4）三唑并（1,5-c）嘧啶衍生物的合成及抗毒活性
3. Synthesis of New Phosphonate Derivatives of Naphtho[2,1-b[Pyran]3,2-e][1,2,4]Triazolo [1,5-c]Pyrimidines [J] . Anis Romdhanea Jean-FranÃ§ois Gallardb Mâhamed Ali Hamzaa amp, Hichem Ben Janneta Phosphorus, Sulfur, and Silicon and the Related Elements . 2012,第5期

机译：萘并[2,1-b [吡喃] 3,2-e] [1,2,4]三唑并[1,5-c]嘧啶的新的膦酸酯衍生物的合成
4. Synthesis and properties for benzotriazole nitrogen oxides (BTzO) and tris1,2,4triazolo1,3,5triazine derivatives [C] . Yanyang Qu, Qun Zeng, Jun Wang, Seminar on New Trends in Research of Energetic Materials . 2016

机译：苯并三唑氮氧化物（BTzO）和三1,2,4三唑并1,3,5三嗪衍生物的合成及性能
5. Synthesis of Fused Triazolo-Pyridobenzodiazepine Analogs for Use as Potential Atypical Antipsychotic Treatments in Schizophrenia. [D] . Sheehan, Megan. 2016

机译：融合的Triazolo-吡啶基苯并二氮杂pine类似物的合成，可用作精神分裂症的潜在非典型抗精神病药物。
6. The Influence of the 1-(3-Trifluoromethyl-Benzyl)-1H-Pyrazole-4-yl Moiety on the Adenosine Receptors Affinity Profile of Pyrazolo[4,3-e][1,2,4]Triazolo[1,5-c]Pyrimidine Derivatives [O] . Stephanie Federico, Sara Redenti, Mattia Sturlese, 2010

机译：1-（3-三氟甲基苄基）-1H-吡唑-4-基对吡唑并[4,3-e] [1,2,4]三唑[1,5-]的腺苷受体亲和力的影响c]嘧啶衍生物
7. Heteroaromatization with 4-Hydroxycoumarin Part II: Synthesis of Some New Pyrano[2,3-d]pyrimidines, [1,2,4]triazolo[1,5-c]pyrimidines and Pyrimido[1,6-b]-[1,2,4]triazine Derivatives [O] . A. H. Bedair, A. H. Fakery, N. A. El-Hady, 2001

机译：4-羟基香豆素的异芳构化第二部分：一些新的吡喃并[2,3-d]嘧啶，[1,2,4]三唑并[1,5-c]嘧啶和嘧啶并[1,6-b] - [1]的合成，2,4]三嗪衍生物

Synthesis of novel fused coumarine and naphtho[2,1-b]pyrano[3,2-e][1,2,4] triazolo[1,5-c]pyrimidine derivatives

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